us.trintellix.comTRINTELLIX (vortioxetine) | Major Depressive Disorder Treatment (MDD)

Important Safety Information Medication Guide Prescribing Information For Healthcare Professionals About MDD What is MDD? Symptom checklist Treatment options Caregiver support About TRINTELLIX How TRINTELLIX works MDD treatment & TRINTELLIX Side effects Real patient stories Hear from real patients Resources Doctor discussion guide Mindfulness tips Additional resources Medication reminder FAQs Savings & more TRINTELLIX cost Savings card & support Important Safety Information Medication Guide Prescribing Information For Healthcare Professionals Menu You are about to leave us.trintellix.com. You are being directed to the product website intended for healthcare professionals. Continue Cancel What is TRINTELLIX ® (vortioxetine)? TRINTELLIX is a prescription medicine used in adults to treat a certain type of depression called Major Depressive Disorder (MDD). TRINTELLIX has not been shown to be safe and effective for use in children. How TRINTELLIX works Patient portrayal. Individual results may vary. How can we help? Select the description that resonates with you, and we’ll provide helpful tools and resources below. Select the description that resonates with you, and we’ll provide helpful tools and resources below. I’m ready to learn more about MDD for myself or a loved one I’m ready to find out more about TRINTELLIX I’ve been prescribed TRINTELLIX and want to know what to expect when getting started About MDD Major Depressive Disorder is anything but simple—it is a complex condition that varies from person to person. Learn more about MDD Symptom checklist MDD is more than just sadness and has multiple symptoms. This checklist can help you better understand yours. Start your checklist Hear from real MDD patients Get an inside look at the lives of real MDD patients, and how they worked with their doctor to manage their MDD. Hear their stories Doctor discussion guide Get a personalized guide to support a conversation with your doctor about whether TRINTELLIX may be right for you. Start now Side effects It’s important to know the possible side effects of a treatment when considering your options. See side effects Patient stories Get an inside look at the lives of real MDD patients, and how they worked with their doctor to manage their MDD. Hear their stories Cost savings and support Eligible patients may pay as little as $10 for either a 30-day or 90-day prescription with the TRINTELLIX Savings Card. † † Restrictions apply. Confirm eligibility Patient stories Get an inside look at the lives of MDD patients, and how they worked with their doctor to manage their MDD. Hear their stories Side effects It’s important to be prepared when starting a new medication. See side effects Stay connected Sign up for tips, advice, information and patient stories to help you on your treatment journey. First name Last name Email By checking this box and clicking the "Sign up" button, you certify that you are 18+ years of age and give permission to use your personal information to receive product and disease state information from Takeda Pharmaceuticals U.S.A., Inc., its affiliates, service providers, and co-promotion partners. You may opt out of these communications at any time by clicking on the unsubscribe link in the e-mail communications. All personal information you have provided will be kept confidential and will not be used or distributed for any purpose other than what is explained in our Privacy Notice. We encourage you to read our Privacy Notice by clicking on this link: Takeda Privacy Notice (opens in a new tab) . This consent will be in effect until such time as you opt out. Sign up We’re sorry, there has been an issue with submitting your information. . This email address was not recognized. Please check your spelling and try again. The TRINTELLIX Savings & Support Program Did you know you may pay as little as $10 for either a 30‑day or 90‑day prescription with the TRINTELLIX Savings Card? * * Even if you’re not currently prescribed TRINTELLIX, you can still receive support. By enrolling in tAccess (at no cost to you), you can customize your experience through support tools like chats with an advisor, texts and emails. *All TRINTELLIX patients can join the tAccess Support Program. Only commercially insured patients ages 18 and older are eligible for the TRINTELLIX Savings Card. The TRINTELLIX Savings Card cannot be used by patients in federal-, state-, or government-funded healthcare programs, or by cash patients. Savings of up to $100 per 30-day or $300 per 90-day prescription, with maximum total savings of $1,300 over one year. Restrictions apply. See Savings Card for full Eligibility Requirements and Terms & Conditions. Learn about tAccess The TRINTELLIX Savings & Support Program Did you know you may pay as little as $10 for either a 30‑day or 90‑day prescription with the TRINTELLIX Savings Card? * * Even if you’re not currently prescribed TRINTELLIX, you can still receive support. By enrolling in tAccess (at no cost to you), you can customize your experience through support tools like chats with an advisor, texts and emails. *All TRINTELLIX patients can join the tAccess Support Program. Only commercially insured patients ages 18 and older are eligible for the TRINTELLIX Savings Card. The TRINTELLIX Savings Card cannot be used by patients in federal-, state-, or government-funded healthcare programs, or by cash patients. Savings of up to $100 per 30-day or $300 per 90-day prescription, with maximum total savings of $1,300 over one year. Restrictions apply. See Savings Card for full Eligibility Requirements and Terms & Conditions. Learn about tAccess Still have questions? Check out our FAQ page for answers. Get answers IMPORTANT SAFETY INFORMATION about TRINTELLIX Expand IMPORTANT SAFETY INFORMATION Suicidal Thoughts & Actions TRINTELLIX and other antidepressants increase the risk of suicidal thoughts and actions in people 24 years of age and younger, especially within the first few months of treatment or when the dose is changed. TRINTELLIX is not for use in children. Depression or other mental illnesses are the most important causes of suicidal thoughts or actions. Pay close attention to any changes, especially new or sudden changes in mood, behavior, thoughts, or feelings, or if you develop suicidal thoughts or actions. Call your doctor or get emergency help right away to report any of these, or if you have symptoms such as suicidal thoughts or actions, impulsivity, aggressive or violent actions, depression, anxiety or panic attacks, agitation, restlessness, anger, irritability, trouble sleeping, an increase in activity or talking, or other unusual changes in behavior or mood; especially if they are new, worse, or worry you. Who should not take TRINTELLIX? Do not start or take TRINTELLIX if you: are allergic to vortioxetine or any of the ingredients in TRINTELLIX are taking, or have stopped taking within the last 14 days, a medicine called a Monoamine Oxidase Inhibitor (MAOI), including the antibiotic linezolid or intravenous methylene blue Do not start taking an MAOI for at least 21 days after you stop treatment with TRINTELLIX. What should I tell my doctor before taking TRINTELLIX? Before taking TRINTELLIX, tell your doctor: about all your medical and other health conditions if you are pregnant or plan to become pregnant, since TRINTELLIX may harm your unborn baby. Taking TRINTELLIX during your third trimester may cause your baby to have withdrawal symptoms after birth or to be at increased risk for a serious lung problem at birth. Tell your doctor right away if you become or think you are pregnant while taking TRINTELLIX if you are breastfeeding or plan to breastfeed, since it is not known if TRINTELLIX passes into your breast milk Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements, since TRINTELLIX and some medicines may cause serious side effects (or may not work...